Biosensor for the detection of protein kinase A, and kit comprising the same
AssigneeKorea Institute of Science and Technology
InventorsEun-Gyeong Yang, Ki-Cheol Han, Dae-Sung Yoon, Tae-Song Kim
Life of this patent
Estimating the term…
Abstract
The present invention relates to a biosensor specifically detecting a protein kinase A (PKA), and a diagnosis kit comprising the biosensor. In particular, the present invention relates to a biosensor for detecting a PKA comprising a cantilever, and a protein kinase inhibitor (PKI) immobilized on the surface of the cantilever; and a kit for diagnosing diseases caused by the increase of the activity of a protein kinase, comprising a sample, the biosensor, and a quantification manner.
Claims13
A biosensor for detecting protein kinase A comprising a cantilever, and a protein kinase inhibitor peptide having 20 to 76 amino acid residues comprising at least 20 amino acid residues from 5th to 24th amino acids of SEQ ID NO:
- 1 immobilized on the cantilever.
The kit according to 11, wherein the disease is selected from the group consisting of cancers, cardiovascular syndromes, immunological diseases, hormonal disorders, apoplexy, and infectious diseases.
The kit according to 11, further comprising ATP solution having the concentration of 10 to 1000 μM.
Dependencies are inferred from the claim text.