84P2A9: a prostate and testis specific protein highly expressed in prostate cancer
AssigneeAgensys, Inc.
InventorsAya Jakobovits, Daniel E. H. Afar, Pia M. Challita-Eid, Elena Levin, Steven Chappell Mitchell, Rene S. Hubert
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Abstract
A novel gene (designated 84P2A9) and its encoded protein is described. While 84P2A9 exhibits prostate and testis specific expression in normal adult tissue, it is aberrantly expressed multiple cancers including prostate, testis, kidney, brain, bone, skin, ovarian, breast, pancreas, colon, lymphocytic and lung cancers. Consequently, 84P2A9 provides a diagnostic and/or therapeutic target for cancers, and the 84P2A9 gene or fragment thereof, or its encoded protein or a fragment thereof used to elicit an immune response.
Claims10
An isolated polynucleotide that encodes the polypeptide sequence of SEQ ID NO:2.
An isolated polynucleotide comprising
- the sequence set forth in SEQ ID NO:1 from nucleotide residue number 720 through nucleotide residue number 1392.
Dependencies are inferred from the claim text.