EphB receptor-binding peptides
AssigneeBurnham Institute for Medical Research
InventorsElena B. Pasquale, Mitchell Koolpe
Life of this patent
Estimating the term…
Abstract
The application is related to the identification of peptides that selectively bind to Eph receptors of the B class. Also disclosed are uses of such peptides in the treatment of a variety of diseases. Additionally, imaging tumors in patients is described by administrating labeled peptides to patients and then obtaining an image of the labeled peptides.
Claims17
An isolated peptide which selectivity binds to an EphB4 receptor and inhibits binding of Ephrin B2 ligand to said EphB4 receptor, wherein said peptide consists of less than 25 amino acid residues and has the amino acid sequence of SEQ ID NO:39.
Dependencies are inferred from the claim text.