Methods of organ regeneration using Hox 11-expressing pluripotent cells
AssigneeThe General Hospital Corporation
InventorDenise L. Faustman
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Abstract
The invention features methods for increasing or maintaining the number of functional cells of a predetermined type in a mammal (e.g., a human patient), for example, the insulin producing cells of the pancreas, liver cells, spleen cells, or bone cells, that has injured or damaged cells of the predetermined type or is deficient in cells of the predetermined type.
Claims21
A method for increasing or maintaining the number of functional pancreatic islet cells in a pancreas of a human, wherein said pancreas is injured, damaged, or deficient in said pancreatic islet cells, said method comprising administering to said human a composition enriched in pluripotent cells that express the Hox11 gene.
Dependencies are inferred from the claim text.