Nanofiber surfaces for use in enhanced surface area applications
AssigneeNanosys, Inc.
InventorsRobert Dubrow, Robert Hugh Daniels
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Abstract
This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates, as well as methods and uses for such substrates.
Claims13
A drug delivery device for introduction of one or more substances into a subject, which device comprises a substrate made from a first material, which substrate comprises:
- at least a first surface, a plurality of semiconductor nanofibers attached to the first surface which nanofibers are made from a second compositionally different material from the first material, a reservoir of the one or more substances comprised between the members of the plurality of nanofibers, and the one or more substance incorporated into the reservoir such that said one or more substances is at least partially shielded from direct exposure to bodily fluids within the subject when the device is introduced into the subject.
A method of suppressing the formation of a biofilm on a medical device in a subject, the method comprising providing one or more surface of the medical device, growing a plurality of semiconductor nanofibers on at least a portion of the one or more surface of the medical device, which nanofibers have an external surface that is functionalized with one or more functional groups that render the external surface of the nanofibers hydrophobic and which surface of the medical device comes into contact with the subject, wherein members of the plurality of nanofibers comprise an average length of from about 1 micron to at least about 200 microns;
- an average diameter of from about 5 nm to at least about 1 micron, and an average density of from about 1 nanofiber per square micron to at least about 1000 nanofibers per square micron.
Dependencies are inferred from the claim text.