Methods and compositions for regenerating tissue
AssigneeThe United States of America as represented by the Department of Vetrans Affairs
InventorCatherine A. Phillips
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Abstract
The present invention is directed to methods for delivering cells to a target tissue in a mammal using glycoconjugate to traffic the cell to a desired organ in the mammal. The methods according to the present invention are especially applicable to administering stem cells such as those derived from the bone marrow or from umbilical cord tissue. The methods are also useful for targeting a gene of interest to a tissue in a mammal by introducing a cell containing the gene of interest and administering a glycoconjugate to the mammal.
Claims6
A method for regenerating heart tissue in a mammalian subject which comprises administering to the subject a composition comprising asialoorosomucoid and a composition comprising asialodeterminant-bearing stem cells selected from the group consisting of CD34+ stem cells and hematopoietic stem cells, whereby heart tissue is regenerated.
Dependencies are inferred from the claim text.