Reactor for solid phase synthesis
AssigneeHoffmann-La Roche Inc.
InventorsMartin Blum, Gerald Zieres
Life of this patent
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Abstract
A Reactor (1) for solid phase synthesis comprises a vessel (2), a plurality of filters (3) arranged in the vessel (2) and a plurality of filtrate outlets (4) for evacuating the filtrate out of the filters (3). Each filter (3) is connected to one filtrate outlet (4). The reactor (1) comprises means (3, 4) for delivering a gas into the vessel (2) in a region of the vessel (2) near to the bottom (24) of the vessel (2) and beside the filters (3).
Claims6
A reactor for solid phase synthesis comprising vessel having a bottom, a filter arranged in the vessel and a filtrate outlet connected to the filter for evacuating a filtrate out of the filter, and means for delivering a gas into the vessel in a region of the vessel near the bottom of the vessel and beside the filter,
- wherein the filter comprises a filter cartridge, and
- wherein further the filter cartridge has an intermediate bottom that separates the filter cartridge into a lower chamber connected to the filtrate outlet and an upper chamber;
- and a one-way valve that connects the upper chamber with the lower chamber such that the intermediate bottom of the filter cartridge is pervious in the direction from the upper chamber to the lower chamber but not in the direction from the lower chamber to the upper chamber.
A reactor for solid phase synthesis comprising a vessel having a bottom, a filter arranged in the vessel and a filtrate outlet connected to the filter for evacuating a filtrate out of the filter, and means for delivering a gas into the vessel in a region of the vessel near the bottom of the vessel and beside the filter, wherein the vessel comprises an exhaust connected to the means for delivering the gas such that exhausted gas can return back into the vessel.
A reactor for solid phase synthesis comprising a vessel having a bottom, a filter arranged in the vessel and a filtrate outlet connected to the filter for evacuating a filtrate out of the filter, and means for delivering a gas into the vessel in a region of the vessel near the bottom of the vessel and beside the filter, further comprising a cascade of vessels each comprising an exhaust, wherein each vessel is connected together in such a way that the exhaust of one vessel is connected to the means for delivering the gas of the following vessel.
Dependencies are inferred from the claim text.