Method for the production on metal carboxylates and the metal aminoate or metal hydroxy analogue methionate derivatives thereof, and use of same as growth promoters in animal feed
AssigneeNorel
InventorEnrique Pablos
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Abstract
A process for preparing a feed supplement that promotes growth in animals by (i) preparing a dry metal carboxylate of formula M(RCOOH)2; (ii) preparing a metal aminoate; and (iii) mixing the dry metal carboxylate and the metal aminoate under conditions that form a complex including the metal carboxylate and the metal aminoate and water, then removing the water to form a dry metal complex of the metal carboxylate and the metal aminoate. When administered to an animal in its feed, a bioavailability of the divalent metal in the dry metal complex is different than the bioavailability of the divalent metal in either the dry metal carboxylate or the metal aminoate alone.
Claims23
A process for preparing a feed supplement that promotes growth in animals comprising the steps of:
- (i) preparing a dry metal carboxylate of formula M(RCOOH)2, wherein M is a Zn2+ or Cu2+ cation of a divalent metal and R is H or a CH3(CH2)2 group, by (a) mixing a carboxylic acid with a basic salt of the divalent metal to form a first reaction mixture that undergoes an exothermic reaction to form the metal carboxylate and water, and (b) stirring to remove water;
- (ii) preparing a metal aminoate by (a) mixing water, a compound comprising the divalent metal, and an amino acid selected from the group consisting of glycine and methionine to form a second reaction mixture, (b) stirring the second reaction mixture to promote an exothermic reaction that forms the metal aminoate and water, and (c) removing water from the second reaction mixture;
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- (iii) mixing the dry metal carboxylate and the metal aminoate under conditions that form a complex comprising the metal carboxylate and the metal aminoate and water, and removing the water to form a dry metal complex of the metal carboxylate and the metal aminoate, wherein, when administered to an animal in its feed, a bioavailability of the divalent metal in the dry metal complex is different than the bioavailability of the divalent metal in either the dry metal carboxylate or the metal aminoate alone.
A process for preparing a compound that promotes growth in animals comprising the steps of:
- (i) mixing a carboxylic acid selected from the group consisting of formic acid and butyric acid with a hydroxy analog of methionine to form a first mixture;
- (ii) mixing the first mixture with a basic compound of a divalent metal comprising Zn2+ or Cu2+ to form a reaction mixture that undergoes an exothermic reaction to form a complex comprising a carboxylate- methioninate hydroxy analog of the divalent metal and water, and
- (iii) removing water to recover a dry metal complex of the carboxylate and methioninate hydroxy analog, wherein, when administered to an animal in its feed, a bioavailability of the divalent metal in the dry metal complex is different than the bioavailability of the divalent metal in either the dry metal carboxylate or the metal aminoate alone.
An animal feed supplement comprising a complex of a divalent metal carboxylate and an aminoate or hydroxyl analog thereof, wherein the bioavailability of the divalent metal in the complex is better than the bioavailability of the divalent metal in the carboxylate alone.
Dependencies are inferred from the claim text.