Automated analysis of complex matrices using mass spectrometer
AssigneesMDS Analytical Technologies, Applera Corporation
InventorByron Kieser
Life of this patent
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Abstract
Improved systems, apparatus, methods, and programming useful for the automated analysis of complex compounds using mass spectrometers. Systems, apparatus, methods, and programming according to the invention provide for the automatic determination by a controller 54 of a mass spectrometer 14, 214 of an analysis operation to be implemented using the mass spectrometer, the analysis operation adapted specifically for analysis of one or more substances based contained within a compound based on identification of the compound and/or substances provided by a user of the spectrometer, and a database 66 or other library of information concerning suitable processes or process steps for analyzing substances.
Claims9
A method of controlling a mass spectrometer in the analysis of a compound, the method performed by a controller of an automated mass analyzer and comprising:
- receiving from an input source signals representing an identifier identifying a compound comprising a plurality of substances;
- using the identifier, automatically accessing data comprising analysis parameters associated with the identifier and, using the accessed data, automatically determining a set of command signals for use by a mass spectrometer in analyzing at least a portion of the compound;
- and
- providing the command signal set to the mass spectrometer, in order to configure the mass spectrometer to analyze at least a portion of the compound.
A system useful for the automated analysis of compounds using a mass spectrometer, the system comprising:
- a mass spectrometer adapted to receive ions from ion source,
- a controller adapted to receive from an input source signals representing an identifier identifying a compound comprising a plurality of substances;
- to use the identifier to automatically access data comprising analysis parameters associated with the identifier and, using the accessed data, to automatically determine a set of command signals for use by a mass spectrometer in analyzing at least a portion of the compound;
- and to provide output signals representing the command signal set to the mass spectrometer, for use by the mass spectrometer in analyzing at least a portion of the compound.
A computer usable medium having computer readable code embodied therein for causing a controller for a mass analysis system to:
- receive from an input source signals representing an identifier identifying a compound comprising a plurality of substances;
- using the identifier, automatically access data comprising analysis parameters associated with the identifier and, using the accessed data, automatically determine a set of command signals for use by a mass spectrometer in analyzing at least a portion of the compound;
- and
- provide the command signal set to the mass spectrometer, for use by the mass spectrometer in analyzing at least a portion of the compound.
Dependencies are inferred from the claim text.