Back to results
US 7,547,786 B2Granted
Process for producing thiazole derivative
AssigneeDaiichi Sankyo Company, Limited
InventorsHiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
Life of this patent
Estimating the term…
Abstract
The present invention provides processes for producing a compound (5) based on the following reaction scheme.
Claims4
A process for producing a compound of formula (5) or a salt thereof comprising:
- reacting a compound of formula (1) or a salt thereof
- with sulfur powder and cyanamide in the presence of a secondary amine, to thereby obtain a compound of formula (2) or a salt thereof;
- reacting the obtained compound (2) or a salt thereof, hydrobromic acid and alkali metal nitrite, to thereby obtain a compound of formula (3) or a salt thereof;
- and reacting the obtained compound (3) or a salt thereof with an alkyllithium and carbon dioxide to obtain the compound of formula (5).
1 more element
Dependencies are inferred from the claim text.