Magnetic nanoparticles and method for producing the same
AssigneeNational Cheng Kung University
InventorsDong-Hwang Chen, Yang-Chuang Chang
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Abstract
Magnetic nanoparticles and a method for producing the same are disclosed. A carboxylated polysaccharide with various functions such as chelating and ion exchange is covalently bound on the surfaces of magnetic nanoparticles. The polysaccharide-bound magnetic nanoparticles are highly stable, well dispersed, and have many advantages of high adsorption capacity, fast adsorption rate and easy magnetically manipulation. Hence, the polysaccharide-bound magnetic nanoparticles are applied to adsorb many ionic substances, and further act as an adsorbent for wastewater treatment or biochemical separation, a carrier for drugs or gene site-directed delivery, and a magnetic resonance imaging (MRI) contrast agent.
Claims9
Polysaccharide-bound magnetic nanoparticles, each comprising:
- a magnetic nanoparticle;
- and
- carboxylated chitosan or derivatives thereof, encapsulating the magnetic nanoparticle.
A method for producing polysaccharide-bound magnetic nanoparticles, comprising the steps of:
- forming a magnetic nanoparticle;
- providing chitosan or derivatives thereof;
- conducting a carboxylation process on the chitosan or derivatives thereof;
- and
- covalently binding a carboxylated chitosan or derivatives thereof to a surface of the magnetic nanoparticle through activation with carbodiimide.
Dependencies are inferred from the claim text.