Macromolecular ketoaldehydes
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsMitchell J. Poss, Henk Blom, Alex Odufu, Robert Smakman
Life of this patent
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Abstract
Methods of producing macromolecular compositions and using same are provided. The method includes preparing a resin material; forming an acetyl group on the resin material; and oxidizing the acetyl group via a one-step reaction including reacting a sulfoxide and an acid with the acetyl group to form a ketoaldehyde group. The macromolecular compositions are capable of removing an effective amount of one or more constituents from a physiological solution, such as urea during dialysis therapy.
Claims2
A macromolecular composition comprising:
- polystyrene;
- a spacer group attached to a phenyl group of the polystyrene, wherein the spacer group is selected from the group consisting of a substituted or an unsubstituted aliphatic group, a substituted or an unsubstituted alicyclic group, a substituted or an unsubstituted aromatic group and combinations thereof;
- and
- an alpha-ketoaldehyde group attached to the spacer group.
A macromolecular composition comprising:
- polystyrene;
- a spacer group attached to a phenyl group of the polystyrene, wherein the spacer group comprises a methylene group;
- and
- an alpha-ketoaldehyde group attached to the spacer group.
Dependencies are inferred from the claim text.