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US 7,544,177 B2Granted
Aerosol device to deliver bioactive agent
AssigneeThe Regents of the University of California
InventorMichael E. Gertner
Life of this patent
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Abstract
This invention provides surgical devices and methods to apply bioactive agents to surgical sites. The devices include, e.g., a body for attachment of a pressurized fluid vessel and a reservoir of bioactive agent for controlled spraying of an aerosol of bioactive agent.
Claims25
A device comprising:
- a body with means for receiving a pressurized fluid vessel;
- a pressurized fluid vessel in communication with said means for receiving a pressurized fluid vessel;
- a means for receiving a reservoir containing a bioactive agent;
- a reservoir containing a bioactive agent in communication with said means for receiving a reservoir containing a bioactive agent;
- a mixing chamber;
- a nozzle in communication with said mixing chamber;
- a valve for regulating the flow of pressurized fluid into said mixing chamber and out said nozzle;
- and
- a valve for regulating the flow of bioactive agent into said mixing chamber;
- whereby said device can deliver a pressurized gas stream for cleaning a surgical site and/or a pressurized gas stream containing said bioactive agent, wherein said bioactive agent is selected from the group consisting of a hemostatic agent, an adhesion preventing compound, a nucleic acid, a protein, a muscle contraction stimulator, an anti-inflammatory compound, a vaccine, an enzyme, a growth factor, a nanoparticle, and a pharmaceutical.
7 more elements
Dependencies are inferred from the claim text.