Automatic liquid injection system and method
AssigneeBracco Research S.A.
InventorsMichel Schneider, Laurent Jakob, Christophe Golay, Jean Brochot, Feng Yan
Life of this patent
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Abstract
A power assisted method and injector device for controllably delivering to patients a dispersion medicament or diagnostically active agent, the homogeneity of which is preserved throughout delivery. Diagnostically active agents disclosed are gas microbubble suspensions useful in ultrasonic diagnostic imaging and liposomal formulations in which liposome vesicles are loaded with iodinated compounds.
Claims31
A method of administering to patients by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, said method comprising:
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogeneous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing said distribution
- wherein said rotation or rocking motion is not caused by vibration produced by a motor unconnected to the syringe.
A method of administering to patients by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, said method comprising:
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogeneous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing said distribution
- wherein said rotation or rocking motion is caused by rotating or rocking the injector system or the syringe by a motor connected to said injector system or to said syringe respectively.
A method of imaging organs, blood vessels or tissues of a mammal comprising administering to the mammal by injection or infusion a suspension of microparticles homogenously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, comprising:
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogenous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing their distribution, wherein said rotation or rocking motion is caused by rotating or rocking the injector system or the syringe by a motor connected to said injector system or to said syringe, respectively, and thereafter
- imaging the mammal.
A method of imaging organs, blood vessels or tissues of a mammal comprising administering to the mammal by injection or infusion a suspension of microparticles homogenously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, comprising:
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogenous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing their distribution, wherein said rotation or rocking motion is not caused by vibration produced by a motor unconnected to the syringe and thereafter
- imaging the mammal.
A method of CT imaging organs, blood vessels or tissue of a mammal comprising administering to the mammal by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, said method comprising
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogenous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing their distribution, wherein said rotation or rocking motion is not caused by vibration produced by a motor unconnected to the syringe, and thereafter
- imaging the mammal.
A method of CT imaging organs, blood vessels or tissue of a mammal comprising administering to the mammal by injection or infusion a suspension of microparticles homogeneously distributed in an aqueous liquid carrier by means of an injector system comprising a syringe containing said suspension and a power driven piston for injecting said suspension into a patient, said method comprising
- subjecting the suspension in the syringe to a rotation or rocking motion, thereby maintaining said suspension homogenous by preventing segregation of the microparticles by gravity or buoyancy, and without damaging said particles or disturbing their distribution, wherein said rotation or rocking motion is caused by rotating or rocking the injector system or the syringe by a motor connected to said injector system or to said syringe, respectively, and thereafter
- imaging the mammal.
Dependencies are inferred from the claim text.