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US 7,531,512 B2Granted
Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes
AssigneeUniversity of Maryland, Baltimore
InventorsAlessio Fasano, Tammara L. Watts
Life of this patent
Estimating the term…
Abstract
A method for preventing or delaying the onset of autoimmune diseases is disclosed.
Claims12
A method for delaying progression of diabetes, comprising:
- administering to a diabetic patient, a pharmaceutically effective amount of a peptide antagonist of zonulin, wherein the peptide antagonist binds to zonula occludens toxin receptor but does not physiologically modulate the opening of mammalian intestinal tight junctions.
A method for delaying progression of diabetes, comprising:
- administering to the small intestine of a diabetic patient, a pharmaceutically effective amount of a peptide consisting essentially of the amino acid sequence of SEQ ID NO:
- 15.
Dependencies are inferred from the claim text.