Method of treating abnormal tissue in the human esophagus
AssigneeBarrx Medical, Inc.
InventorsRobert A. Ganz, Brian D. Zelickson, Roger A. Stern
Life of this patent
Estimating the term…
Abstract
An ablation catheter system and method of use is provided to endoscopically access portions of the human esophagus experiencing undesired growth of columnar epithelium. The ablation catheter system and method includes controlled depth of ablation features and use of either radio frequency spectrum, non-ionizing ultraviolet radiation, warm fluid or microwave radiation, which may also be accompanied by improved sensitizer agents.
Claims51
A method of ablating mucosal tissue in an esophagus, comprising:
- providing an energy delivery device;
- positioning at least a portion of the energy delivery device at a mucosal tissue surface of the esophagus;
- delivering sufficient energy from the energy delivery device to the mucosal tissue surface to create a lesion in the mucosal tissue, while controlling a depth of the lesion.
A method of treating a tissue site in an esophagus, comprising:
- providing a dilation and ablation catheter having a balloon member;
- providing an energy delivery device having a plurality of RF electrodes positioned on an outside surface of the balloon member;
- positioning at least a portion of the energy delivery device at a mucosal surface of the tissue site in the esophagus;
- expanding the balloon member in the esophagus;
- delivering sufficient energy from the energy delivery device to create a lesion with a controlled depth in the mucosal tissue.
The method of 30, where at least a portion of the plurality of RF electrodes are bi-polar RF electrode pairs.
The method of 31, wherein adjacent RF electrodes are spaced apart by a distance in the range of 0.3mm to 2mm.
A method for treating a tissue site in the esophagus, comprising:
- providing an energy delivery device that includes a plurality of RF electrodes, a width of each RF electrode and a spacing between adjacent RF electrodes being selected to control a depth of ablation in mucosal layer of the esophagus;
- positioning at least a portion of the energy delivery device at the tissue site in the esophagus;
- delivering sufficient energy from the energy delivery device to create a desired ablation depth in the mucosal layer.
Dependencies are inferred from the claim text.