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US 7,528,131 B2Granted
Substituted morpholinyl compounds
AssigneeConcert Pharmaceuticals, Inc.
InventorsRose A. Persichetti, Scott L. Harbeson
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Abstract
This disclosure relates to novel substituted morpholinyl compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a 5HT4 serotonin receptor agonist.
Claims11
A compound of Formula A:
- or a pharmaceutically acceptable salt, hydrate or solvate thereof, wherein:
- R1 is ethyl wherein from 1 to 5 hydrogen atoms are optionally replaced with deuterium;
- and
- each of R2a, R2b, R3a, R3b, R4a, R4b, R4c, and R4d is independently selected from H and D;
- and
- at least one R comprises a deuterium atom.
3 more elements
Dependencies are inferred from the claim text.