PLGA substrate with aligned and nano-sized surface structures and associated method
AssigneePurdue Research Foundation
InventorsGrace E. Park, Brian C. Ward, Kinam Park, Thomas J. Webster
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Abstract
A substrate for promoting growth of chondrocytes to repair articular cartilage is disclosed. The substrate comprises a polymeric material comprising aligned and nano-sized surface structures. An associated method is disclosed.
Claims12
A substrate for promoting growth of chondrocytes to repair articular cartilage, the substrate comprising a polymeric material, wherein said polymeric material comprises aligned and nano-sized surface structures formed on the surface of said polymeric material of said substrate, said nano-sized surface structures comprising grooves and protrusions, wherein the grooves have a maximum depth, and the protrusions have a maximum height, of less than 100 nm.
A substrate comprising a polymeric material with nano-sized surface structures, wherein a dimension of the nano-sized surface structures is less than 100 nm, said dimension selected from the group consisting of cross-sectional diameter and height.
A substrate comprising a polymeric material wherein the surface of said polymeric material comprises nano-sized protrusions and grooves, wherein a dimension of said protrusions and grooves is less than 100 nm.
Dependencies are inferred from the claim text.