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AssigneeCardiomedics, Inc.
InventorsMarvin P. Loeb, Ginger Johnson, John P. Burrell, Robert J. Sullivan, Lawrence J. Perkins
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A method for treating patients suffering from left ventricular dysfunction, exhibited by a left ventricular ejection fraction (LVEF) less than normal, is disclosed. The method involves applying, during diastole, for a time period of about one hour, about five days each week for at least about seven weeks, an incrementally increasing therapeutic pressure to the patients' lower extremities, from the calves through the thighs and the buttocks. The hourly treatments are carried out at incrementally increasing peak diastolic/systolic pressure ratios (D/S Ratios) in the range of about 0.4:1 up to about 0.6:1 and thereafter at a D/S Ratio in the range of 0.5:1 to 1:1 for each consecutive hourly treatment, with the proviso that the average D/S Ratio over the entire treatment regimen does not exceed about 0.9:1.
A method for treating a patient exhibiting left ventricular dysfunction and having a left ventricular ejection fraction of no more than about 40 percent of left ventricle volume, but at least 15 percent of left ventricle volume, which comprises applying, during diastole, for a time period of about one hour, about five days each week for at least about seven weeks, an incrementally increasing external therapeutic pressure using a plurality of cuffs, sequentially to the lower extremities of the patient, beginning with a first hourly treatment at a D/S Ratio in the range of about 0.4:1 up to about 0.6:1 and thereafter at a D/S Ratio in the range of about 0.5:1 to about 1:1 for each consecutive hourly treatment, with the proviso that the average D/S Ratio over the entire treatment does not exceed about 0.9:1.
Dependencies are inferred from the claim text.