KDR peptides and vaccines comprising the same
AssigneeOncotherapy Science, Inc.
InventorsHideaki Tahara, Satoshi Wada, Takuya Tsunoda
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Abstract
The present invention provides nonapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO: 2, 3, 5, 8, 11, or 12; nonapeptides or decapeptides selected from peptides comprising the amino acid sequence of SEQ ID NO: 29, 30, 33, 34, 40, or 46; and peptides with cytotoxic T cell inducibility, in which one, two, or several amino acids are substituted or added to the above-mentioned amino acid sequences, as well as pharmaceuticals for treating or preventing tumors, where the pharmaceuticals comprise these peptides. The peptides of this invention can be used as vaccines.
Claims10
An isolated nonapeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 30, and SEQ ID NO:
- 54, wherein zero, one or two amino acids have been substituted, wherein the nonapeptide binds to an HLA-A 0201 restricted T cell receptor with high affinity and induces a high CTL response.
Dependencies are inferred from the claim text.