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US 7,485,283 B2Granted
Contrast agents for myocardial perfusion imaging
AssigneeLantheus Medical Imaging, Inc.
InventorsHeike S. Radeke, David S. Casebier, Michael T. Azure, Douglas D. Dischino
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Abstract
The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.
Claims3
A contrast agent of formula (IV)
- wherein
- n, m, and o are independently 1, 2, 3, or 4;
- Z is O, S, or NR46;
- R45 is an imaging moiety or C1-C4 alkyl optionally substituted with an imaging moiety;
- R45 is hydrogen or C1-C3 alkyl;
- Ar is phenyl, furyl, thienyl, oxazolinyl, isoxazolinyl, thiazolyl, isothiazolyl, pyridyl, naphthyl, pyrimidinyl, or pyrazinyl;
- G is absent or O;
- and
- L is an imaging moiety;
- provided that when G is absent, o is 3.
7 more elements
A contrast agent which is
A contrast agent which is
Dependencies are inferred from the claim text.