Human and murine Mus81 proteins
AssigneesThe Scripps Research Institute, Janssen Pharmaceutica NV
InventorsPaul R. Russell, Jorge E. Vialard, Michael N. Boddy, Paul A. Shanahan, Antonia Lopez-Girona, Cecile-Marie D. D. Denis, Clare H. McGowan
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Abstract
The present invention encompasses novel mammalian cell cycle checkpoint genes/DNA repair genes, cDNA or genomic DNA, isolated nucleic acids corresponding thereto, proteins encoded thereby, expression vectors comprising said nucleic acids, host cells transformed with said expression vectors, and methods for treating a cell using such nucleic acids or proteins.
Claims6
An isolated human Mus81 protein, said protein comprising the amino acid sequence selected from the group of SEQ ID NO:
- 2, SEQ ID NO:
- 4, SEQ ID NO:
- 8, and SEQ ID NO:
- 10.
An isolated murine Mus81 protein, said protein comprising the amino acid sequence selected from the group of SEQ ID NO:
- 12, SEQ ID NO:
- 14, SEQ ID NO:
- 16, and SEQ ID NO:
- 18.
Dependencies are inferred from the claim text.