Photodynamic therapy in selective cell inactivation in blood and treating immune dysfunction diseases
AssigneesQLT Inc., The University of British Columbia
InventorsSimon Leong, Agnes How-Ching Chan, David William Carey Hunt, Julia G. Levy, Martin Renke, Janice North
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Abstract
Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.
Claims10
A method for ameliorating the physiological effects of multiple sclerosis, which method comprises
- a) administering to a subject in need of such amelioration an amount of a photoactive compound effective to distribute in said subject;
- b) allowing said distribution to occur;
- and
- c) irradiating the subject with light absorbed by said photoactive compound at an intensity sufficient to activate said photoactive compound to effect its toxicity.
Dependencies are inferred from the claim text.