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US 7,479,480 B2Granted
Peptides that promote lipid efflux
AssigneeLipid Sciences, Inc.
InventorH. Bryan Brewer, Jr.
Life of this patent
Estimating the term…
Abstract
Disclosed herein are peptides with domains that promote lipid efflux from cells and optionally possess at least one anti-inflammatory domain or a domain that stimulates LCAT activity. Provided herein are methods of using the peptides to treat or inhibit diseases including dyslipidemic disorders, stroke and myocardial infarction. Also provided are methods of detecting plaque in vessels using the labeled peptides of the present invention.
Claims6
An isolated peptide comprising SEQ ID NO:
- 142 Ser Pro Leu Leu Glu Ser Ala Lys Val Ser Ala Leu Ser Ala Leu Glu Glu Ala Thr Lys Lys Lys Leu Ser Pro Leu Leu Glu Ser Phe Lys Val Ser Phe Leu Ser Ala Leu Glu Glu Tyr Thr Lys Lys Leu Asn Thr Gln.
Dependencies are inferred from the claim text.