HXHV virus, nucleic material, peptide material and uses
AssigneeInstitut National de la Recherche Medicale
InventorsIsabelle Chemin, Christian Trepo, Frederic Bedin, Colette Jolivet Reynaud
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Abstract
Isolated HXHV virus having the following characteristics: (i) a DNA genome which is at least partially single-stranded, (ii) the said genome comprises one reading frame (ORF) encoding one protein or one polyprotein (iii) the said genome comprises a nucleotide sequence which exhibits, for any segment of at least 40 nucleotides belonging to the said sequence, at least 90% homology with SEQ ID NO: 1 or with its complementary sequence, nucleic material and peptide material and uses.
Claims18
An isolated DNA nucleotide fragment, comprising a nucleotide sequence of at least 40 contiguous nucleotides belonging to the segment starting at nucleotide 813 and ending at nucleotide 1361 of the sequence set forth in SEQ ID NO:
- 1, or the complementary sequence of said segment.
An isolated DNA nucleotide fragment, comprising a nucleotide sequence of at least 40 contiguous nucleotides belonging to the segment starting at nucleotide 927 and ending at nucleotide 968 of the sequence set forth in SEQ ID NO:
- 1, or the complementary sequence of said segment.
An isolated DNA nucleotide fragment, comprising the sequence set forth in SEQ ID NO:
- 1 or its full-length complementary sequence.
A method of detecting HXHV DNA or RNA in a biological sample, comprising:
- (i) Contacting a sample suspected of containing HXHV nucleic acid with at least one probe or primer comprising 12 or more contiguous nucleotides of the segment of nucleotides 813-1361 of SEQ ID NO:
- 1 or the complement thereof, and then
- (ii) demonstrating hybridization of said probe or primer to said HXHV DNA or RNA or amplification of said HXHV DNA or RNA,
- wherein demonstration of said hybridization or amplification indicates the presence of HXHV DNA or RNA.
Dependencies are inferred from the claim text.