Method to detect lung cancer
AssigneeWayne State University
InventorMaik Huttemann
Life of this patent
Estimating the term…
Abstract
Certain embodiments of the present invention relate to methods for detecting lung cancer.
Claims21
A method for detecting the presence of lung cancer in a first biological sample, comprising determining the level of RNA for isoform 2 of subunit 4 of cytochrome c oxidase (COX4-2) in the first biological sample, wherein a lower level of COX4-2 RNA in the first biological sample as compared to the level of COX4-2 RNA in a second biological sample that does not comprise lung cancer indicates the presence of lung cancer in the first biological sample, wherein the first and second biological sample comprises lung cells.
A method for screening a subject at risk for developing lung cancer, comprising determining the level of RNA for isoform 2 of subunit 4 of cytochrome c oxidase (COX4-2) in a biological sample from the subject, wherein a lower level of COX4-2 RNA in the sample as compared to the level of COX4-2 RNA in a biological sample that does not comprise lung cancer indicates that the subject has lung cancer, wherein the biological sample comprises lung cells.
A method for identifying and treating lung cancer in a subject, comprising determining the level of RNA for isoform 2 of subunit 4 of cytochrome c oxidase (COX4-2) in a biological sample from the subject, wherein a lower level of COX4-2 RNA in the sample as compared to the level of COX4-2 RNA in a biological sample that does not comprise lung cancer indicates that the subject has lung cancer, and administering a treatment for lung cancer to the subject, wherein the biological sample comprises lung cells.
A method for determining whether a subject has lung cancer, comprising determining the level of RNA for isoform 2 of subunit 4 of cytochrome c oxidase (COX4-2) in a biological sample from the subject, wherein a lower level of COX4-2 RNA in the sample as compared to the level of COX4-2 RNA in a biological sample that does not comprise lung cancer indicates that the subject has developed lung cancer, wherein the biological sample comprises lung cells.
Dependencies are inferred from the claim text.