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US 7,473,417 B2Granted
Inherently radiopaque bioresorbable polymers for multiple uses
AssigneeREVA Medical, Inc.
InventorsJoan Zeltinger, Donald K. Brandom
Life of this patent
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Abstract
Preferred embodiments of the present invention relate to polymeric medical devices, such as stents. More particularly, the compositions disclosed herein comprise halogen-containing phenol moeities, that may be used for medical devices and other uses whereby bioresorbable and radiopaque and physicomechanical properties are desired.
Claims30
An inherently radiopaque, biocompatible, bioresorbable polymer, wherein said polymer comprises one or more recurring units of the Formula (I):
- wherein:
- X1 and X2 are each independently selected from the group consisting of Br and I;
- y1 and y2 are each independently zero or an integer in the range of 1 to 4, with the proviso that the sum of y1 and y2 is at least 1;
- R1is
- R13 and R14 are each independently selected from the group consisting of —CH═CH—, —(CH2)c—, —(CHJ1)—, —CHJ2—CHJ3—,—CH═CH—(CHJ1)—, and (CH2)c—(CHJ1)—;
- c is zero or an integer in the range of 1 to 8;
- J1, J2, and J3 are each independently selected from the group consisting of H, Br, I, —NH—Q2 and —C(═Z8)—OQ3;
- Q1, Q2 and Q3 are each independently H or a non-crystallizable group comprising from about 1 to about 30 carbons;
- Z7 and Z8 are each independetly O or S;
- A1 is selected from the group consisting of
- R5 is selected from the group consisting of H, C1-C30 alkyl, and C1-C30 heteroalkyl.
8 more elements
Dependencies are inferred from the claim text.