# US 7,465,471 B2 · Palatability of aquaculture feed

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 7,465,471 B2
- Document ID: US7465471B2
- Status: Granted
- Kind: B2
- Application number: 11/078,093
- Filed: 2005-03-11
- Published: 2005-09-29
- Granted: 2008-12-16
- Earliest claimed: 2003-03-21
- Assignees: Novus International, Inc.
- Inventors: Andrew F. Giesen; Mercedes Vazquez-Anon
- Web page: https://patentgrep.com/patent/US7465471B2

## CPC

- A01N 37/46: N-acyl derivatives
- A01N 37/36: containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A23K 20/105: Aliphatic or alicyclic compounds
- A23K 30/00: Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K 50/80: for aquatic animals, e.g. fish, crustaceans or molluscs
- A61K 31/35: having six-membered rings with one oxygen as the only ring hetero atom
- Y10S 426/805: Pet food for dog, cat, bird, or fish
- Y10S 426/807: Poultry or ruminant feed
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A23K: FODDER
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- Y10S: TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

## Abstract

A method for enhancing the palatability of aquaculture food, the method comprising treating the food with a compound of Formula I: wherein R1, R2, R3, and n are as defined herein, are disclosed.

## Claims

### Claim 1

A method for enhancing the palatability of feed for aquaculture, the method comprising treating the feed with a compound of formula I:
wherein R1 is an alkyl group having from one to four carbon atoms;
n is an integer from 0 to 2;
R2 is selected from the group consisting of hydroxy, —OCOR3, or —NHCOR3;
and wherein R3 is an organic acid derivative;
or a salt thereof;
wherein the concentration of the compound of formula I in the feed is from about 0.005 wt. % to about 0.5 wt. %; wherein the contacts of said aquaculture with said aquaculture food during a unit time are increased relative to the contacts of the same aquaculture with an aquaculture food otherwise identical but lacking said compound of formula I.

### Claim 2 (depends on 1)

The method of claim 1 wherein said compound of Formula I is 2-hydroxy-4-(methylthio)butanoic acid, or a salt, ester or amide thereof.

### Claim 3 (depends on 1)

The method of claim 1 wherein said concentration of the compound of formula I is from about 0.01 wt. % to about 0.04 wt. %.

### Claim 4 (depends on 1)

The method of claim 1 wherein said feed for aquaculture is fed to fish comprising fish other than catfish and salmon.

### Claim 5 (depends on 4)

The method of claim 4 wherein said feed for aquaculture is fed to carp.

### Claim 6

A method of feeding fish comprising administering a fish food comprising a compound of formula I:
wherein R1 is an alkyl group having from one to four carbon atoms;
n is an integer from 0 to 2;
R2 is selected from the group consisting of hydroxy, —OCOR3, or —NHCOR3;
and wherein R3 is an organic acid derivative;
or a salt thereof;
wherein the concentration of said compound of formula I is effective to enhance the palatability of said fish food; such that the contacts of said fish with said fish food during a unit time are increased relative to the contacts of the same fish with a fish food otherwise identical but lacking said compound of formula I.

### Claim 7 (depends on 6)

The method of claim 6 wherein said compound of Formula I is 2-hydroxy-4-(methylthio)butanoic acid, or a salt, ester or amide thereof.

### Claim 8 (depends on 6)

The method of claim 6 wherein the concentration of the compound of formula I is from about 0.001 wt. % to about 1.0 wt. %.

### Claim 9 (depends on 8)

The method of claim 8 wherein the concentration of the compound of formula I is from about 0.01 wt. % to about 0.07 wt. %.

### Claim 10 (depends on 6)

The method of claim 6 wherein said fish food is fed to carp, catfish, tilapia, salmon, trout, smelt, shrimp or prawns.

### Claim 11 (depends on 10)

The method of claim 10 wherein said fish food is fed to carp.