# US 7,465,050 B2 · Method and apparatus for three-dimensional video-oculography

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- Number: US 7,465,050 B2
- Document ID: US7465050B2
- Status: Granted
- Kind: B2
- Application number: 10/588,738
- Filed: 2005-02-04
- Published: 2007-08-02
- Granted: 2008-12-16
- Earliest claimed: 2004-02-04
- Assignees: The Johns Hopkins University
- Inventors: Americo A. Migliaccio; Charles C. Della Santina; Hamish G. MacDougall
- Web page: https://patentgrep.com/patent/US7465050B2

## CPC

- A61B 3/113: for determining or recording eye movement
- A61B 3/145: {by video means}
- A61B 5/11: Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb {(A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721)}
- G06F 3/013: {Eye tracking input arrangements (G06F3/015 takes precedence)}
- A61B 5/1114: {Tracking parts of the body}
- A61B 5/4023: {Evaluating sense of balance}
- A61B 5/6803: {Head-worn items, e.g. helmets, masks, headphones or goggles}
- A61B 5/6814: {Head}
- A61B 5/6831: {Straps, bands or harnesses}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)

## Abstract

A device for measuring the three-dimensional movements of an eye includes: (a) a mark array that identifies prescribed positions on the eye whose movements are to be measured, (b) a digital camera for capturing the two-dimensional images of this marker array as the eye is moved, (c) a light source that illuminates the marker array with an output that is outside the spectral range of the camera, (d) light source that are used to align the camera's optical axis with the center of the eye, (e) an algorithm for computing the three-dimensional positions of the marker array from the information contained in the captured digital images , and (f) a base for fixing the position of the camera relative to the position of the eye, wherein the materials of the marker array are chosen so that the array has the ability to, when illuminated as described above, give off energy that is in the spectral range of the device's camera.

## Claims

### Claim 1

A device for measuring the three-dimensional, rotational movements of an eye, said device comprising: a means for marking an array of positions on said eye whose rotational movements are to be measured, a means for capturing the two-dimensional, digital images of said array of eye-marked positions as said eye is moved, said image capturing means having an optical axis and a prescribed spectral range, a means for illuminating said marker array with a light source whose output is in a spectral range that is chosen from the group consisting of those that are either within or outside of said spectral range of said image capturing means, a means for aligning said optical axis of said image capturing means with the center of said eye, and a means for computing the three-dimensional rotational movements of said array of eye-marked positions from the information contained in said captured digital images.

### Claim 2 (depends on 1)

The device as recited in claim 1, further comprising a means for fixing the position of said image capturing means relative to the position of said eye whose movements are to be measured.

### Claim 3 (depends on 1)

The device as recited in claim 1, wherein said alignment means including an alignment light source.

### Claim 4 (depends on 2)

The device as recited in claim 2, wherein said alignment means including an alignment light source.

### Claim 5 (depends on 1)

The device as recited in claim 1, wherein said array marking means including a fluorescent pigment.

### Claim 6 (depends on 5)

The device as recited in claim 5, wherein said array illuminating means including an ultra-violet light source.

### Claim 7 (depends on 2)

The device as recited in claim 2, wherein said array marking means including a fluorescent pigment.

### Claim 8 (depends on 7)

The device as recited in claim 7, wherein said array illuminating means including an ultra-violet light source.

### Claim 9 (depends on 3)

The device as recited in claim 3, wherein said array marking means including a fluorescent pigment.

### Claim 10 (depends on 9)

The device as recited in claim 9, wherein said array illuminating means including an ultra-violet light source.

### Claim 11 (depends on 1)

The device as recited in claim 1, wherein said array marking means including an anti-Stokes fluorescent pigment.

### Claim 12 (depends on 11)

The device as recited in claim 11, wherein said array illuminating means including an infrared light source.

### Claim 13 (depends on 2)

The device as recited in claim 2, wherein said array marking means including an anti-Stokes fluorescent pigment.

### Claim 14 (depends on 13)

The device as recited in claim 13, wherein said array illuminating means including an infrared light source.

### Claim 15 (depends on 3)

The device as recited in claim 3, wherein said array marking means including an anti-Stokes fluorescent pigment.

### Claim 16 (depends on 15)

The device as recited in claim 15, wherein said array illuminating means including an infrared light source.

### Claim 17 (depends on 1)

The device as recited in claim 1, wherein said means of marking an array of positions on said eye whose movements are to be measured having three markers arranged in a 45 degree right triangle.

### Claim 18 (depends on 17)

The device as recited in claim 17, wherein said means of computing the locations of said markers having an algorithm having a rotation matrix that describes the eye rotation required to move said markers from a first position to a second position.

### Claim 19 (depends on 1)

The device as recited in claim 1, wherein said image capturing means having a digital camera, a computer processor and a high-speed interfacing device that connects said camera and said processor.

### Claim 20 (depends on 19)

The device as recited in claim 19, wherein said processor being configured to fit within a computer chosen from the group herein described as a desktop, laptop, notebook or sub-miniature notebook.
