Method for creating and using a treatment protocol

A computer program product for implementing a method for performing a risk assessment concerning a subject, the computer program product being suitable for use in connection with a computing environment having a database associated therewith, and the computer program product comprising:

• a computer readable medium carrying computer executable instructions for performing the method, wherein the method comprises:
• receiving results of a viral diagnostic test;
• receiving a status of a culture for identifying the existence or absence of at least one bacterial pathogen;
• receiving results of clinical analysis;
• and
• determining a risk of occurrence, in the subject, of a particular condition of interest, the risk determination being based at least in part upon:
• results of the viral diagnostic test;
• the clinical analysis;
• and, the status of the culture for identifying the existence or absence of at least one bacterial pathogen;
• and
• correlating the risk of occurence of the particular condition with at least one action.

A method for performing a risk assessment concerning a subject, the method being implemented in connection with a client-server computing environment, and the method comprising:

• receiving results of a viral diagnostic test selected from the group consisting of:
• EV PCR, and DFA;
• receiving results of a clinical analysis;
• receiving a status of at least one of:
• hydration, band count, and a culture for identifying the existence or absence of at least one bacterial pathogen;
• and
• determining a risk of occurrence, in the subject, of a particular condition of interest, the risk determination being based at least in part upon:
• results of the viral diagnostic test;
• the clinical analysis;
• and, the status of one or more of the hydration, band count, and culture for identifying the existence or absence of at least one bacterial pathogen.

A computer program product for implementing a method for performing a risk assessment concerning a subject, the computer program product comprising:

• a computer readable medium carrying computer executable instructions for performing the method, wherein the method comprises:
• receiving results of a viral diagnostic test selected from the group consisting of:
• EV PCR, and DFA;
• receiving results of a clinical analysis;
• receiving a status of at least one of:
• hydration, band count, and a culture for identifying the existence or absence of at least one bacterial pathogen;
• and
• determining a risk of occurrence, in the subject, of a particular condition of interest, the risk determination being based at least in part upon:
• results of the viral diagnostic test;
• the clinical analysis;
• and, the status of one or more of the hydration, band count, and culture for identifying the existence or absence of at least one bacterial pathogen.

A method for performing a risk assessment concerning a subject, the method being implemented in connection with a client-server computing environment, and the method comprising:

• receiving results of a DFA viral diagnostic test that tests for at least one of:
• enterovirus, RSV, Influenza A, Influenza B, parainfluenza 1, parainfluenza 2, parainfluenza 3, adenovirus, HHV 6, and rhinovirus;
• receiving results of a Rochester criteria analysis;
• receiving a status of at least one of:
• hydration, band count, a blood culture for identifying the existence or absence of at least one bacterial pathogen, a urine culture for identifying the existence or absence of at least one bacterial pathogen, and a cerebrospinal fluid culture for identifying the existence or absence of at least one bacterial pathogen;
• and
• calculating a risk of occurrence, in the subject, of a bacterial infection, using:
• results of the DFA viral diagnostic test;
• the Rochester criteria analysis;
• and, the status of at least one of said blood, urine, and cerebrospinal fluid cultures, hydration, and band count.

A computer program product for implementing a method for performing a risk assessment concerning a subject, the computer program product being suitable for use in connection with a client-server computing environment, and the computer program product comprising:

• a computer readable medium carrying computer executable instructions for performing the method, wherein the method comprises:
• receiving results of a DFA viral diagnostic test that tests for at least one of:
• RSV, Influenza A, Influenza B, parainfluenza 1, parainfluenza 2, parainfluenza 3, adenovirus, HHV 6, and rhinovirus;
• receiving results of a Rochester criteria analysis;
• receiving a status of at least one of:
• hydration, band count, a blood culture for identifying the existence or absence of at least one bacterial pathogen, a urine culture for identifying the existence or absence of at least one bacterial pathogen, and a cerebrospinal fluid culture for identifying the existence or absence of at least one bacterial pathogen;
• and
• calculating a risk of occurrence, in the subject, of a bacterial infection, using:
• results of the DFA viral diagnostic test;
• the Rochester criteria analysis;
• and, the status of at least one of said blood, urine, and cerebrospinal fluid cultures, hydration, and band count.

A method for calculating a risk that a particular condition will occur in a subject, the method being implemented in connection with a client-server environment having a database associated therewith, the database including viral illness data and bacterial culture data for a plurality of subjects, and the method comprising:

• determining, from the viral illness data of the database, a risk R1 of bacteremia in any given subject testing positive for a viral illness;
• determining, from the bacterial culture data of the database, a risk R2 of a bacterial culture becoming positive for a specified pathogen after a predetermined time period;
• and
• calculating, by multiplying risks R1 and R2 together, a risk R3 of bacteremia in any given subject testing positive for a viral illness and having a negative bacterial culture after expiration of the predetermined time period.

A computer program product for implementing a method for performing a risk assessment concerning a subject, the computer program product being configured to receive data from a database that includes viral illness data and bacterial culture data for a plurality of subjects, the computer program product comprising:

• a computer readable medium carrying computer executable instructions for performing the method, wherein the method comprises:
• determining, from the viral illness data of the database, a risk R1 of bacteremia in any given subject testing positive for a viral illness;
• determining, from the bacterial culture data of the database, a risk R2 of a bacterial culture becoming positive for a specified pathogen after a predetermined time period;
• and
• calculating, by multiplying risks R1 and R2 together, a risk R3 of bacteremia in any given subject testing positive for a viral illness and having a negative bacterial culture after expiration of the predetermined time period.

A method for facilitating development of a treatment protocol, the method being implemented in connection with a computing environment having a database associated therewith that includes viral illness data and bacterial culture data for a plurality of subjects, the method comprising:

• accessing viral infection test results from the viral illness data, the viral infection test results including at least one of an EV PCR and DFA test result for each of the plurality of subjects;
• accessing time to positivity data from the bacterial culture data, the time to positivity data including the results of at least one of a urine, blood, and CSF culture for each of the plurality of subjects;
• statistically analyzing the accessed viral infection test results and the accessed time to positivity data to identify the occurrence of viral infections and the occurrence bacterial infections in the plurality of subjects;
• assessing, based upon the statistical analysis, the risk of a subject that has a viral illness also having a concomitant bacterial illness;
• and
• using the risk assessment to define a rule suitable for use as part of the treatment protocol for treating subsequent subjects at risk for bacterial infection.

A computer program product for use in a computer system, the computer program product for implementing a method for facilitating development of a treatment protocol, the computer program product being configured to receive data from a database that includes viral illness data and bacterial culture data for a plurality of subjects, and the computer program product comprising:

• a recordable-type computer readable medium carrying computer executable instructions that, when executed at a processor, cause the computer system to perform the method, including the following:
• accessing viral infection test results from the viral illness data, the viral infection test results including at least one of an EV PCR and DFA test result for each of the plurality of subjects;
• accessing time to positivity data from the bacterial culture data, the time to positivity data including the results of at least one of a urine, blood, and CSF culture for each of the plurality of subjects;
• statistically analyzing the accessed viral infection test results and the accessed time to positivity data to identify the occurrence of viral infections and the occurrence bacterial infections in the plurality of subjects;
• assessing, based upon the statistical analysis, the risk of a subject that has a viral illness also having a concomitant bacterial illness;
• and
• using the risk assessment to define a rule suitable for use as part of the treatment protocol for treating subsequent subjects at risk for bacterial infection.

In a computing environment having a database associated therewith, a method for refining an assessment of risk for bacterial infection in a febrile infant as medical information for the febrile infant becomes available, the method comprising:

• an act of accessing Rochester criteria data including historical data and physical examination data corresponding to a febrile infant;
• an act of assessing a risk of occurrence of a bacterial infection in the febrile infant based on the historical data and physical examination data;
• an act of accessing Rochester criteria data including laboratory result data corresponding to the febrile infant subsequent to accessing the Rochester criteria data including the historical data and the physical examination data;
• an act of re-assessing the risk of occurrence of a bacterial infection in the febrile infant based on the laboratory result data in combination with the historical data and the physical examination data;
• an act of accessing viral diagnostic test result data corresponding to the febrile infant subsequent to accessing the Rochester criteria data including the laboratory result data;
• an act of re-assessing the risk of occurrence of a bacterial infection in the febrile infant based on the viral diagnostic test result data in combination with the laboratory result data, the historical data, and the physical examination data;
• an act of accessing bacterial culture result data corresponding to the febrile infant subsequent to accessing the viral diagnostic test result data;
• and
• an act of re-assessing the risk of occurrence of a bacterial infection in the febrile infant based on the bacterial culture result data in combination with the viral diagnostic result data, the laboratory result data, the historical data, and the physical examination data.

A computer program product for use in a computing environment having a database associated therewith, the computer program product for implementing a method for refining an assessment of risk for bacterial infection in a febrile infant as medical information for the febrile infant becomes available, the computer program product comprising one or more computer-readable media have stored thereon computer-executable instructions that, when executed at a processor, cause the computing environment to perform the method including the following:

• access Rochester criteria data including historical data and physical examination data corresponding to a febrile infant;
• assess a risk of occurrence of a bacterial infection in the febrile infant based on the historical data and physical examination data;
• access Rochester criteria data including laboratory result data corresponding to the febrile infant subsequent to accessing the Rochester criteria data including the historical data and the physical examination data;
• re-assess the risk of occurrence of a bacterial infection in the febrile infant based on the laboratory result data in combination with the historical data and the physical examination data;
• access viral diagnostic test result data corresponding to the febrile infant subsequent to accessing the Rochester criteria data including the laboratory result data;
• re-assess the risk of occurrence of a bacterial infection in the febrile infant based on the viral diagnostic test result data in combination with the laboratory result data, the historical data, and the physical examination data;
• access bacterial culture result data corresponding to the febrile infant subsequent to accessing the viral diagnostic test result data;
• and
• re-assess the risk of occurrence of a bacterial infection in the febrile infant based on the bacterial culture result data in combination with the viral diagnostic result data, the laboratory result data, the historical data, and the physical examination data.