Process for the preparation of glycidyl derivatives
AssigneeRstech Co., Ltd.
InventorsSeong-Jin Kim, Ho-Seong Lee, Jin-Won Yun, Ho-Cheol Kim
Life of this patent
Estimating the term…
Abstract
There is provided a process for preparing a glycidyl derivative from 3-chloro-1,2-propanediol, comprising i) adding a phosphate salt to a solution into which 3-chloro-1,2-propanediol is dissolved into a solvent to produce glycidol, and ii) adding to the solution of step i) a base capable of releasing a glycidyl group from the glycidol and a substrate susceptible to nucleophilic attack to produce the desired glycidyl derivative by nucleophilic attack of the glycidyl group to the substrate.
Claims12
A process for preparing a glycidyl derivative from 3-chloro-1,2-propanediol, comprising the steps of:
- (i) adding a tribasic alkali phosphate salt to a solution into which 3-chloro-1,2-propanediol is dissolved into a solvent to produce glycidol;
- and,
- (ii) adding to the solution of step (i) a base capable of releasing a glycidyl group from the glycidol and a substrate susceptible to nucleophilic attack selected from the group consisting of an acyl halide, an acid anhydride and a sulfonyl halide to produce the desired glycidyl derivative by nucleophilic attack of the glycidyl group to the substrate.
A method for preparing glycidol which comprises treating 3-chloro-1,2-propanediol with a basic salt, characterized in that the basic salt is a tribasic alkali phosphate salt.
Dependencies are inferred from the claim text.