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US 7,459,558 B2Granted
Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
InventorsPierre Etienne Chabrier de Lassauniere, Serge Auvin, Dennis Bigg, Michel Auquet, Jeremiah Harnett
Life of this patent
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Abstract
A method of treating in a warm-blooded animal comprising administering to a warm-blooded animal in need thereof an amount of a compound of the formula wherein the substituents are defined in accordance with the disclosure.
Claims4
A compound of the formula
- wherein
- A is
- X is —CO— or —NH—CO—;
- and Y is —NH—Z2—Q— or piperazine, Q is selected from the group consisting of a single bond, O—Z3, R3—N—Z3 and S—Z3, and Z2 and Z3 are independently a bond or alkylene of 1 to 6 carbon atoms and R3 is hydrogen or alkyl of 1 to 6 carbon atoms;
- B is alkyl of 1 to 6 carbon atoms or carbocyclic or heterocyclic aryl with 5 to 6 members containing 1 to 4 heteroatoms selected from the group consisting of O, S and N, the aryl being optionally substituted by at least one member selected from the group consisting of alkyl, alkenyl and alkoxy of up to 6 carbon atoms;
- R6 is hydrogen or OH;
- and salts thereof.
4 more elements
Dependencies are inferred from the claim text.