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US 7,459,156 B2Granted
Antibodies that mimic actions of neurotrophins
AssigneeThe Regents of the University of California
InventorsDouglas O. Clary, Gisela Weskamp, LeeAnn R. Austin, Louis F. Reichardt
Life of this patent
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Abstract
The use and production of immunoglobulins which activate trk receptors and imitate effects of neurotrophins are provided. Immunoglobulins which block trk receptor activation and methods of use are also provided.
Claims8
A method of therapy for a neurologic disorder associated with suboptimal activity of a trk raceptor, said method comprising administering to a mammal having the disorder a therapeutically effective amount of a multivalent immunoglobulin which activates the receptor.
Dependencies are inferred from the claim text.