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US 7,459,142 B2Granted
High viscosity embolizing compositions comprising prepolymers
AssigneeMicro Therapeutics, Inc.
InventorRichard J. Greff
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Abstract
Disclosed are novel high viscosity compositions for embolizing blood vessels which comprise a biocompatible prepolymer and a contrast agent, and optionally a thickening agent and/or a biocompatible solvent. Also disclosed are methods for embolizing a vascular site by injecting high viscosity prepolymer compositions into said site. The disclosed compositions and methods are particularly well suited for the treatment of aneurysms.
Claims14
A method for embolizing a vascular site, said method comprising:
- (a) selecting an embolic composition comprising
- a cyanoacrylate prepolymer and/or partially reacted monomers and oligomers thereof;
- a biocompatible contrast agent, in an amount capable of being monitored during injection;
- and
- a thickening agent which is a polyacrylate polymer,
- wherein the viscosity of said composition prior to injection is at least about 150 centistokes at 40° C.;
- (b) transferring the embolic composition to a delivery catheter having a proximal end and a distal end, wherein the distal end of the delivery catheter is positioned at the vascular site to be embolized;
- and
- (c) injecting the embolic composition into said vascular site in sufficient amounts to embolize said vascular site.
6 more elements
Dependencies are inferred from the claim text.