Back to results
US 7,454,094 B2Granted
Optical reader system and method that uses non-coherent illumination and angular filtering to interrogate a label independent biosensor
AssigneeCorning Incorporated
InventorsJacques Gollier, Gordon M. Shedd
Life of this patent
Estimating the term…
Abstract
An optical reader system and method are described herein that directs a non-coherent light towards a biosensor, collects the non-coherent light which is reflected (or transmitted) from (or through) the biosensor, and then angularly filters the collected non-coherent light to obtain a narrow spectral response which can be analyzed to determine if a biological substance is located on the biosensor or if a biomolecular event took place on the biosensor.
Claims17
An optical reader system, comprising:
- a launch system that directs a non-coherent light which is diverging when received by a biosensor;
- and
- a receive system that collects the non-coherent light from the biosensor where the collected non-coherent light has multiple wavelengths and each wavelength has a specific angle and then the receive system angularly filters the collected non-coherent light such that the angularly filtered non-coherent light has only one specific angle which is detected and the detected angularly filtered non-coherent light has a resonance wavelength which is analyzed to determine if a biological substance is present on the biosensor or if a biomolecular event took place on the biosensor.
A method for interrogating a biosensor, said method comprising the steps of:
- directing a non-coherent light which is diverging when received by a biosensor;
- collecting the non-coherent light from the biosensor, where the collected non-coherent light has multiple wavelengths and each wavelength has a specific angle;
- angularly filtering and the collected non-coherent light such that the angularly filtered non-coherent light has only one specific angle;
- detecting the angularly filtered non-coherent light;
- and
- analyzing a resonance wavelength of the detected non-coherent light to determine if a biological substance is present on the biosensor or if a biomolecular binding event took place on the biosensor.
3 more elements
Dependencies are inferred from the claim text.