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US 7,453,555 B2Granted
Aggregometer with near ultraviolet light source
AssigneeBio/Data Corporation
InventorsWilliam E. Coville, Donald G. Ware
Life of this patent
Estimating the term…
Abstract
An aggregometer has a radiation path along which radiation can pass, a sample receiving area located along the radiation path, a short-wavelength LED that transmits radiation along the radiation path through the sample receiving area, a detector positioned along the radiation path for detecting radiation transmitted from the short-wavelength LED, and a processor that controls intensity of radiation transmitted from the short-wavelength LED.
Claims12
A method for testing a fluid comprising:
- providing a plasma sample including an un-reacted reagent;
- transmitting a beam of short-wavelength radiation through the plasma sample at a predetermined transmission level;
- detecting an attenuation of the beam of radiation at the predetermined transmission level through the un-reacted plasma sample;
- detecting an attenuation of the beam of radiation at the predetermined transmission level through the plasma sample during a period of reaction of the reagent in the plasma sample;
- and
- comparing the attenuation of the beam of radiation through the plasma sample during the reaction period with the beam of radiation during the period of non-reaction.
3 more elements
A method for testing a fluid comprising the steps of:
- providing a sample including an un-reacted reagent;
- transmitting a beam of short-wavelength radiation through the sample at an original transmission intensity;
- detecting an attenuated intensity of the beam of short-wavelength radiation after the beam of short-wavelength radiation passes through the un-reacted reagent;
- increasing the transmission intensity of the beam of short-wavelength radiation until the attenuated intensity corresponds to the original transmission intensity;
- allowing the un-reacted reagent to react;
- and
- detecting a subsequent attenuated intensity of the beam of short-wavelength radiation after the beam of short-wavelength radiation at the predetermined transmission level passes through the reagent during a time period while the reagent is reacting.
4 more elements
A method for testing a fluid comprising the steps of:
- providing a substantially platelet-free plasma sample;
- transmitting a beam of short-wavelength radiation through the substantially platelet-free plasma sample at an original transmission intensity;
- detecting an attenuated intensity of the beam of short-wavelength radiation after the beam of short-wavelength radiation passes through the substantially platelet-free plasma sample;
- providing a plasma sample with substantially unaggregated platelets;
- transmitting a beam of short-wavelength radiation through the sample with substantially unaggregated platelets at the original transmission intensity;
- detecting an attenuated intensity of the beam of short-wavelength radiation after the beam of short-wavelength radiation passes through the plasma sample with substantially unaggregated platelets;
- and
- detecting an attenuated intensity of the beam of short-wavelength radiation after the beam of short-wavelength radiation passes through the plasma sample during a period of aggregation of the platelets.
5 more elements
Dependencies are inferred from the claim text.