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US 7,452,866 B2Granted
Methods of inhibiting angiogenesis with fragments and homologs of troponin subunit 1
AssigneesChildren's Medical Center Corporation, Alseres Pharmaceuticals, Inc.
InventorsRichard M. Thorn, Mark A. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
Life of this patent
Estimating the term…
Abstract
The present invention relates to methods of inhibiting angiogenesis associated with a disease or disorder with peptides homologous to amino acid residues 130-137 or 132-139 of human troponin subunit I.
Claims17
An isolated peptide consisting of a region of troponin subunit I having amino acid residues 94-123 (huTnl 94-123) of SEQ ID NO:17.
A pharmaceutical composition comprising a peptide consisting of amino acid residues 94-123 (huTnl 94-123) of SEQ ID NO:17 and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.