Nucleic acids encoding T2R of taste receptors
AssigneesThe Regents of the University of California, The United States of America as represented by the Department of Health and Human Services
InventorsCharles S. Zuker, Jon Elliot Adler, Mark Hoon, Nick Ryba, Ken Mueller
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Abstract
The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
Claims8
An isolated nucleic acid encoding a taste transduction G-protein coupled receptor, wherein the receptor is expressed in a taste cell and binds a bitter tastant, the receptor comprising greater than about 95% amino acid sequence identity to SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.