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AssigneeAgouron Pharmaceuticals, Inc.
InventorsChristopher Todd Bauer, Maureen Jeri Bourner, Melanie Boyle, Gerald Fries Casperson, David William Griggs, Richard David Head, William Dean Joy, Richard Allen Mazzarella, Ralph Raymond Minter, Mark Allen Moffat, Barrett Richard Thiele, Todd Lee Vanarsdale
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The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
An isolated antibody or antigen-binding portion thereof that binds to human P-cadherin, wherein said antibody or antigen-binding portion comprises:
An isolated antibody comprising a VH domain as set forth in SEQ ID NO:
An isolated P-cadherin antibody or antigen-binding portion thereof, wherein said antibody is g-194-g09.
Dependencies are inferred from the claim text.