Methods of treatment using CTLA-4 antibodies
AssigneeMedarex, Inc.
InventorsThomas Andrew Davis, Tibor P. Keler, Robert F. Graziano, Alan J. Korman
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Abstract
The present invention provides method of treatment using human sequence antibodies against human CTLA-4. In particular, methods of treating cancer are provided.
Claims18
A method for inducing or enhancing a memory immune response to an antigen in a human patient, which comprises administering to the patient who has developed a primary immune response to the antigen an anti-CTLA-4 antibody such that plasma concentration of the anti-CTLA-4 antibody is maintained above detectable levels for greater than four months.
A method for inducing or enhancing a memory immune response to an antigen in a human patient, which comprises administering to the patient an anti-CTLA-4 antibody such that plasma concentration of the anti-CTLA-4 antibody is maintained above detectable levels for greater than four months.
A method for treating cancer in a human patient by administering to a patient an anti-CTLA-4 antibody such that plasma concentration of the anti-CTLA-4 antibody is maintained above detectable levels for greater than four months.
Dependencies are inferred from the claim text.