Method of producing macedocin by culturing Streptococcus macedonicus
AssigneeVrije Universiteit Brussel
InventorsLuc De Vuyst, Marina Georgalaki, Effie Tsakalidou
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AssigneeVrije Universiteit Brussel
InventorsLuc De Vuyst, Marina Georgalaki, Effie Tsakalidou
Estimating the term…
The invention relates to the field of bacteriocin producing microorganisms. The invention more specifically relates to the characterization of a novel food grade bacteriocin, namely a lantibiotic, named macedocin and produced by Streptococcus macedonicus ACA-DC 198. Macedocin inhibit a broad spectrum of lactic acid bacteria as well as several food spoilage and pathogenic bacteria, among others Clostridium tyrobutyricum, and is heat stable and active in a broad pH range. The invention further relates to the use of non-pathogenic microorganisms for producing macedocin in food fermentation processes, such as for preparing milk products, butter, cheese and fermented meat and vegetables, as well as in non-fermented food products such as raw meat, modified atmosphere-packed meat products, ready-to-eat meals, and canned food products, and its use for the preparation of functional starter cultures and cocultures.
A method for producing the food grade lantibiotic, macedocin, comprising growing a Streptococcus macedonicus ACA-DC 198 strain, deposited under BCCM™/LMG Accession No. LMG-P-21771, in a growth medium comprising 10% wt/vol skim milk supplemented with at least one of the following:
Dependencies are inferred from the claim text.