Painless injectable compositions containing salts of 2-arylpropionic acids
AssigneeDompe S.p.A.
InventorsMarco Maria Gentile, Maria Concetta Dragani
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Abstract
The invention relates to pharmaceutical compositions of alkylammonium salts of 2-aryipropionic acids, including ketoprofen, ibuprofen, naproxen and tiaprofenic acid. The compositions are suitable for parenteral administration arid, due to buffering at pH 8 to 9, cause less pain upon injection than previously known composition.
Claims5
A pharmaceutical composition having anti-inflammatory and analgesic property, comprising an alkylammonium salt of a 2-arylpropionic acid which is a L-lysine salt of ketoprofen in an aqueous solution at a pH in the range from 8 to 9, said solution being free of preservatives and co-solvents, wherein the composition is formulated for parenteral administration.
Dependencies are inferred from the claim text.