Replikin peptides and uses thereof
OwnerSamuel Bogoch, Elenore S. Bogochinventors
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Abstract
The present invention provides a new class of peptides related to rapid replication and high human mortality, and their use in diagnosing, preventing and treating disease.
Claims15
An isolated or synthesized coronavirus peptide consisting of 7 to about 50 amino acids wherein said peptide is isolated or synthesized by identifying a motif consisting of:
- (1) at least one lysine residue located at a first terminus of said motif and at least one lysine residue or at least one histidine residue located at a second terminus of said motif;
- (2) a first lysine residue located six to ten residues from a second lysine residue;
- (3) at least one histidine residue;
- and
- (4) at least 6% lysine residues,
- selecting said identified motif and isolating or synthesizing said coronavirus peptide comprising said identified motif wherein said motif is selected from the group consisting of SEQ ID NO:
- 712, SEQ ID NO:
- 717, SEQ ID NO:
- 718, SEQ ID NO:
- 719, and SEQ ID NO:
- 720.
An immunogenic composition comprising a pharmaceutically acceptable carrier and at least one isolated or synthesized coronavirus Replikin peptide wherein said isolated or synthesized coronavirus Replikin peptide consists of 7 to about 50 amino acids and wherein said coronavirus Replikin peptide is isolated or synthesized by identifying a motif consisting of:
- (1) at least one lysine residue located at a first terminus of said motif and at least one lysine residue or at least one histidine residue located at a second terminus of said motif;
- (2) a first lysine residue located six to ten residues from a second lysine residue;
- (3) at least one histidine residue;
- and
- (4) at least 6% lysine residues,
- selecting said identified motif and isolating or synthesizing said coronavirus peptide comprising said identified motif and wherein said identified motif is selected from the group consisting of SEQ ID NO:
- 712, SEQ ID NO:
- 717, SEQ ID NO:
- 718, SEQ ID NO:
- 719, and SEQ ID NO:
- 720.
Dependencies are inferred from the claim text.