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US 7,442,721 B2Granted
Durable biocompatible controlled drug release polymeric coatings for medical devices
AssigneeMedtronic Vascular, Inc.
InventorsPeiwen Cheng, Mingfei Chen, Kishore Udipi
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Abstract
Disclosed herein are biocompatible durable controlled drug releasing polymeric coatings for medical devices. The drug release rates of the polymers are controlled by adjusting monomer ratios and glass transition temperatures Tgs. The polymers are durable; they do not delaminate from the coated medical device.
Claims14
A durable controlled drug releasing polymeric coating for an implantable medical device comprising:
- a first monomer and optionally a second monomer wherein said first monomer is 2-ethoxyethyl methacrylate and said second monomer is an acrylate monomer;
- and
- a drug,
- wherein said durable controlled drug releasing polymeric coating comprises a drug elution profile selected from the group consisting of a rapid large burst of drug followed by a steady release rate;
- a rapid small burst of drug followed by a steady release rate;
- and a gradual release of drug without a burst.
3 more elements
Dependencies are inferred from the claim text.