Adipogenic adenoviruses as a biomarker for disease
AssigneesObetech, LLC, Obetech Obesity Research
InventorRichard L. Atkinson
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Abstract
This invention relates to the relationship between infection with adipogenic adenoviruses, such as adenovirus-36 (Ad-36) and the etiologies of obesity and obesity-related cancers and other diseases. Additionally, the invention relates to assaying a subject for Ad-36 status and using Ad-36 status as a marker for the presence of cancer, to predict the future risk of developing cancers, such as breast or prostate cancer, and/or to predict the aggressiveness and prognosis of these cancers.
Claims10
A method for predicting cancer aggressiveness in a subject having an abnormality compatible with a tumor, said method comprising the steps of:
- obtaining a sample from the subject;
- assaying the sample to determine whether the subject is infected with an adipogenic adenovirus;
- and
- predicting a more aggressive form of cancer in a subject infected with an adipogenic relative to a subject not infected with an adipogenic adenovirus.
Dependencies are inferred from the claim text.