US 7,442,302 B2 · Highly water-permeable blood purifier of hollow-fiber membrane type

Abstract

The present invention provides a highly water permeable hollow fiber membrane type blood purifier for medical use, which is excellent in safety and module-assembling ease and which has a high water permeability suitable for use in therapy of chronic renal failure. The present invention relates to a highly water-permeable hollow fiber type blood purifier comprising hydrophobic polymer hollow fiber membranes each of which contains a hydrophilic polymer, characterized in that the amount of the hydrophilic polymer eluted from the hollow fiber membrane is 10 ppm or less; in that the ratio of the hydrophilic polymer in the outer surface of the hollow fiber membrane is 25 to 50 mass %; in that the burst pressure of the hollow fiber membrane is 0.5 MPa or higher; and in that the coefficient of water permeability of the blood purifier is 150 ml/m2/hr./mmHg or higher.

Claims7

Dependent claims

A highly water-permeable hollow fiber type blood purifier comprising hydrophobic polymer hollow fiber membranes, each of which contains a hydrophilic polymer,

wherein (i) the amount of the hydrophilic polymer eluted from the hollow fiber membrane is 10 ppm or less;
(ii) the ratio of the hydrophilic polymer in the outer surface of the hollow fiber membrane is 25 to 50 mass %;
(iii) the burst pressure of the hollow fiber membrane is 0.5 MPa or higher;
(iv) the coefficient of water permeability of the blood purifier is 150 ml/m2/hr./mmHg or higher;
and (v) the average hole area of the outer surface of the hollow fiber membrane is 0.3 to 1.0 μm2.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

10/559,398Filed 26 Aug 2004

Priority

JP 2003-20983929 Aug 2003

Published

US 2006/0191844 A131 Aug 2006

Granted

28 Oct 2008

Term ends

Not estimatedThe source records don’t support an estimate.

Classification17 codes

B01D 69/08
Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes…:…
B01D 67/0083
After-treatment of organic or inorganic membranes: thermal after-treatment
B01D 67/0088
After-treatment of organic or inorganic membranes: physical treatment with compounds, e.g. swelling, coating or impregnation
B01D 69/02
Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes…:…

Highly water-permeable blood purifier of hollow-fiber membrane type

Life of this patent

Highly water-permeable blood purifier of hollow-fiber membrane type

Life of this patent

Abstract

Claims7