Analyte filter method and apparatus
AssigneeSensys Medical, Inc.
InventorsTimothy L. Ruchti, Alexander D. Lorenz, Kevin H. Hazen
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Abstract
The invention comprises a method and apparatus for enhancing the analysis of noninvasive spectra, resulting in improved analytical performance. More particularly, the invention comprises a method and apparatus for processing noninvasive spectra with an analyte filter that preferably rejects variation likely to be detrimental to the measurement system, while passing signal that probabilistically is unique to the target analyte. Subsequently, the analyte filtered data are used to estimate an analyte property, such as a glucose concentration, in the presence of noise, interferences, state changes, and/or across analyzers.
Claims78
A method for determining a property of an analyte using a noninvasive spectrum, comprising the steps of:
- processing said noninvasive spectrum using an analyte filter yielding a processed spectrum, wherein said analyte filter correlates with frequency response shape of said analyte;
- generating said analyte filter using a set of spectra from a first set of spectrometers;
- and
- estimating said property using a multivariate model and said processed spectrum.
An apparatus for determining an analyte property using a noninvasive spectrum, comprising:
- means for obtaining said noninvasive spectrum;
- and
- an analyzer, comprising:
- a processor;
- an algorithm executed by said processor;
- an analyte filter operating as a step in said algorithm;
- and
- a multivariate model operating as a step in said algorithm,
- said analyzer operating on said noninvasive spectrum using said analyte filter to yield a processed spectrum;
- said analyte filter correlating with frequency response shape of said analyte;
- and
- said multivariate model operating on said processed spectrum to yield said analyte property;
- wherein said analyte filter is generated using a set of data from a set of spectrometers, wherein said analyzer is not a member of said set of spectrometers.
Dependencies are inferred from the claim text.