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US 7,431,763 B2Granted
Magnesium ammonium phosphate cement composition
AssigneeKyphon SARL
InventorMichael Zimmermann
Life of this patent
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Abstract
This invention relates to a cement, which comprises in its main phase of microcrystalline magnesium ammonium phosphate and nanoapatite after hardening and thus at the same time has considerable strength. The material is biologically degradable and is suitable for application in tooth cements, as bone replacement, as bone filler, as bone cement or as bone adhesive.
Claims38
A magnesium ammonium phosphate cement preparation comprising:
- a) a powder mixture comprising a calcium (Ca) orthophosphate and magnesium (Mg) orthophosphate, wherein the molar quantities of Mg and orthophosphate are in the range Mg/orthophosphate (P)<1.0;
- and molar quantities of Ca and orthophosphate are in the range Ca/orthophosphate (P)<1.5;
- and
- b) an ammonium salt.
1 more element
A magnesium ammonium phosphate cement preparation comprising:
- a) an ammonium salt;
- and
- b) a powder mixture comprising the components calcium (Ca) orthophosphate (P), magnesium (Mg), orthophosphate, and granular particles, wherein the molar quantities of the components Mg and orthophosphate are in the range Mg/orthophosphate (P)<1.0 and molar quantities of Ca and orthophosphate are in the range Ca/orthophosphate (P)<1.5, wherein the granular particles are configured to leach from a hardened cement structure formed from the cement preparation, leaving the hardened cement structure porous.
A magnesium ammonium phosphate cement preparation comprising:
- a) an ammonium salt and/or strontium salt;
- and
- b) a powder mixture comprising calcium (Ca) orthophosphate (P) and magnesium (Mg) orthophosphate, wherein the molar quantities of Ca and orthophosphate are in the range Ca/orthophosphate (P)<1.5 and the molar quantities of the components Mg and orthophosphate are in the range Mg/orthophosphate (P)<1.0, wherein the cement preparation when hardened forms a bone replacement material that stimulates endogenous bone transformation processes and allows for active resorption of the bone replacement material.
Dependencies are inferred from the claim text.