Polysiloxane prepolymers for biomedical devices
AssigneeBausch & Lomb Incorporated
InventorsYu-Chin Lai, Weihong Lang, Edmond T. Quinn
Life of this patent
Estimating the term…
Abstract
A polysiloxane copolymer that is useful for forming biomedical devices comprises blocks (I) and (II) and is terminated at each end with an ethylenically unsaturated radical: (*Dii*Diol*Dii*PS)x (I) (*Dii*PS)y (II) wherein: each Dii is independently a diradical residue of a diisocyanate; each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms; each PS is independently a diradical residue of a polysiloxane-containing diol or diamine; each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—: x represents the number of blocks (I) and is at least 2, and y represents the number of blocks (II) and is at least 1.
Claims24
A copolymer that is the polymerization product of a monomeric mixture comprising a copolymer represented by the general formulae,
- M(*Dii*Diol*Dii*PS)x(*Dii*PS)y*Dii*M or
- M(*Dii*Diol*Dii*PS)x(*Dii*PS)y*Dii*Diol*Dii*M
- wherein:
- each M is independently a polymerizable ethylenically unsaturated radical;
- each Dii is independently a diradical residue of a diisocyanate;
- each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms;
- each PS is independently a diradical residue of a polysiloxane-diol or a polysiloxane diamine;
- each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—;
- x is at least 2, and
- y is at least 1;
- and
- a hydrophilic comonomer and a monofunctional silicone-containing monomer.
A hydrogel copolymer that is the hydrated polymerization product of a monomeric mixture comprising a copolymer represented by the general formulae,
- M(*Dii*Diol*Dii*PS)x(*Dii*PS)y*Dii*M or
- M(*Dii*Diol*Dii*PS)x(*Dii*PS)y*Dii*Diol*Dii*M
- wherein;
- each M is independently a polymerizable ethylenically unsaturated radical;
- each Dii is independently a diradical residue of a diisocyanate;
- each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms;
- each PS is independently a diradical residue of a polysiloxane-diol or a polysiloxane diamine;
- each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—;
- x is at least 2, and
- y is at least 1;
- and
- a hydrophilic comonomer and a monofunctional silicone-containing monomer.
Dependencies are inferred from the claim text.