# US 7,412,286 B2 · Biatrial triple-chamber cardiac pacemaker with multi-conditional inhibition of second atrial stimulation > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 7,412,286 B2 - Document ID: US7412286B2 - Status: Granted - Kind: B2 - Application number: 10/652,861 - Filed: 2003-08-29 - Published: 2004-09-02 - Granted: 2008-08-12 - Earliest claimed: 2002-09-02 - Assignees: BIOTRONIK SE & Co. KG - Applicants: Max Schaldach, Jr., legal representative - Inventors: Ulrich Busch - Web page: https://patentgrep.com/patent/US7412286B2 ## CPC - A61N 1/368: comprising more than one electrode co-operating with different heart regions {(A61N1/3622, A61N1/3627 take precedence)} - A61N 1/3684: {for stimulating the heart at multiple sites of the ventricle or the atrium} - A61N 1/3718: {Monitoring of or protection against external electromagnetic fields or currents} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract A biatrial triple-chamber cardiac pacemaker has at least one sensing unit for sense events of a first atrium and a ventricle of a heart and at least one stimulation unit which is adapted to produce stimulation pulses to a second atrium and the ventricle, and a control which is connected to the sensing unit and the stimulation unit and is adapted to evaluate at least the atrial sense events (AR-Sense) associated with the first atrium and the ventricular sense events (V-Sense) associated with the ventricle, for actuation of the stimulation unit, which is actuated so that the delivery of a left-atrial stimulation pulse is suppressed if previously a ventricular sense event occurs in a crosstalk window which adjoins a postatrial ventricular blanking time and at the same time the distance in respect of time to the last ventricular event ascertained outside a crosstalk window, to the next possible ventricular stimulation event, is greater than a predetermined maximum value. ## Claims ### Claim 1 A biatrial triple-chamber pacemaker for use with a heart having a first and a second atrium and a first and a second ventricle, said pacemaker comprising: at least one sensing unit for sense events of the first atrium and the first ventricle; at least one stimulation unit which is adapted to produce stimulation pulses to the second atrium and the first ventricle; and a control unit which is connected to the sensing unit and the stimulation unit and which is adapted to evaluate, for actuating the stimulation unit, at least the atrial sense events (AR-Sense) associated with the first atrium and the ventricular sense events (V-Sense) associated with the first ventricle; wherein the stimulation unit is actuated with regard to a ventricular escape interval and a postatrial ventricular blanking time such that an occurrence of the atrial sense event (AR-Sense) triggers the ventricular escape interval, at the end of which a ventricular stimulation pulse is triggered if same is not inhibited by an occurrence of the ventricular sense event within the ventricular escape interval and outside the postatrial ventricular blanking time, wherein the stimulation unit is actuated with regard to an interatrial conduction time such that an occurrence of the atrial sense event (AR-Sense) triggers an interatrial conduction timer to create a predetermined AR-AL time interval, at the end of which a stimulation pulse to the second atrium is triggered if the stimulation pulse to the second atrium is not inhibited, and wherein the stimulation unit is actuated such that the delivery of a stimulation pulse to the second atrium is suppressed when previously an occurrence of the ventricular sense event occurs in a crosstalk window which adjoins a postatrial ventricular blanking time and at the same time a time interval, between a last ventricular sensed event occurring outside the crosstalk window and a next possible (scheduled) ventricular stimulation event, is greater than a predetermined maximum value. ### Claim 2 A biatrial triple-chamber cardiac pacemaker for use with a heart having a first and a second atrium and a first and a second ventricle, said pacemaker comprising: at least one sensing unit for sense events of the first atrium and the first ventricle; at least one stimulation unit which is adapted to produce stimulation pulses to the second atrium and the first ventricle; and a control unit which is connected to the sensing unit and the stimulation unit and which is adapted to evaluate, for actuating the stimulation unit, at least the atrial sense events (AR-Sense) associated with the first atrium and the ventricular sense events (V-Sense) associated with the first ventricle; wherein the stimulation unit is actuated with regard to a ventricular escape interval and a postatrial ventricular blanking time such that an occurrence of the atrial sense event (AR-Sense) triggers the ventricular escape interval, at the end of which a ventricular stimulation pulse is triggered if same is not inhibited by an occurrence of the ventricular sense event within the ventricular escape interval and outside the postatrial ventricular blanking time; wherein the stimulation unit is actuated with regard to an interatrial conduction time such that an occurrence of the atrial sense event (AR-Sense) triggers an interatrial conduction timer to create a predetermined AR-AL time interval, at the end of which a stimulation pulse to the second atrium is triggered if the stimulation pulse to the second atrium is not inhibited; and wherein the stimulation unit is actuated such that the delivery of a stimulation pulse to the second atrium is suppressed when a ventricular sense event occurs during an upper tracking interval operating mode in which the cardiac pacemaker works at a predetermined maximum stimulation rate. ### Claim 3 (depends on 2) The pacemaker of claim 2, further comprising: a further sensing unit for sense events of the second atrium, wherein the delivery of a stimulation pulse to the second atrium is suppressed when the further sensing unit produces a signal which is characteristic of a sense event (AL-Sense) of the second atrium within the interatrial conduction time. ### Claim 4 (depends on 3) The pacemaker of claim 3, wherein: the control unit is adapted to calculate the time spacing from a latest secured ventricular event to a next planned ventricular stimulation pulse. ### Claim 5 (depends on 4) The pacemaker of claim 4, wherein: the control unit is adapted to compare the calculated time spacing to a predeterminable maximum value. ### Claim 6 (depends on 5) The pacemaker of claim 5, wherein: the control unit is adapted to switch off interatrial synchronisation in dependence on the comparison between the calculated time spacing and the predetermined maximum value. ### Claim 7 (depends on 1) The pacemaker of claim 1, further comprising: a further sensing unit for sense events of the second atrium, wherein the delivery of a stimulation pulse to the second atrium is suppressed when the further sensing unit produces a signal which is characteristic of a sense event (AL-Sense) of the second atrium within the interatrial conduction time. ### Claim 8 (depends on 1) The pacemaker of claim 1, wherein: the control unit is adapted to calculate the time spacing from a latest secured ventricular event to a next planned ventricular stimulation pulse. ### Claim 9 (depends on 7) The pacemaker of claim 7, wherein: the control unit is adapted to calculate the time spacing from a latest secured ventricular event to a next planned ventricular stimulation pulse. ### Claim 10 (depends on 2) The pacemaker of claim 2, wherein: the control unit is adapted to calculate the time spacing from a latest secured ventricular event to a next planned ventricular stimulation pulse. ### Claim 11 (depends on 8) The pacemaker of claim 8, wherein: the control unit is adapted to compare the calculated time spacing to a predeterminable maximum value. ### Claim 12 (depends on 9) The pacemaker of claim 9, wherein: the control unit is adapted to compare the calculated time spacing to a predeterminable maximum value. ### Claim 13 (depends on 10) The pacemaker of claim 10, wherein: the control unit is adapted to compare the calculated time spacing to a predeterminable maximum value. ### Claim 14 (depends on 11) The pacemaker of claim 11, wherein: the control unit is adapted to switch off interatrial synchronisation in dependence on the comparison between the calculated time spacing and the predetermined maximum value. ### Claim 15 (depends on 12) The pacemaker of claim 12, wherein: the control unit is adapted to switch off interatrial synchronisation in dependence on the comparison between the calculated time spacing and the predetermined maximum value. ### Claim 16 (depends on 13) The pacemaker of claim 13, wherein: the control unit is adapted to switch off interatrial synchronisation in dependence on the comparison between the calculated time spacing and the predetermined maximum value.